MovDisordV3, Main, Exploration, bibRecord, 005399

Bilateral posteroventral pallidotomy in advanced parkinson's disease in three patients

Identifieur interne : 005399 ( Main/Exploration ); précédent : 005398; suivant : 005400

Bilateral posteroventral pallidotomy in advanced parkinson's disease in three patients

Auteurs : Schuurman [Pays-Bas] ; Rob M. A. De Bie [Pays-Bas] ; Johannes D. Speelman [Pays-Bas] ; D. Andries Bosch [Pays-Bas]

Source :

Movement Disorders [ 0885-3185 ] ; 1997-09.

RBID : ISTEX:5EB2019F253C82A9BBA4FA8F4C7F5AF96D6D638F

English descriptors

KwdEn :
- Activities of Daily Living, Age of Onset, Antiparkinson Agents (therapeutic use), Bilateral pallidotomy, Drug Resistance, Dyskinesia, Drug-Induced (surgery), Dystonia (surgery), Female, Follow-Up Studies, Globus Pallidus (surgery), Humans, Hypokinesia (surgery), Levodopa (therapeutic use), Male, Middle Aged, Muscle Rigidity (surgery), Parkinson Disease (drug therapy), Parkinson Disease (surgery), Parkinson's disease, advanced, Pilot Projects, Prospective Studies, Severity of Illness Index, Treatment Outcome.
MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- drug therapy : Parkinson Disease.
- surgery : Dyskinesia, Drug-Induced, Dystonia, Globus Pallidus, Hypokinesia, Muscle Rigidity, Parkinson Disease.
- Activities of Daily Living, Age of Onset, Drug Resistance, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pilot Projects, Prospective Studies, Severity of Illness Index, Treatment Outcome.

Abstract

In this report, we describe the effect of staged bilateral posteroventral pallidotomy in three patients with advanced Parkinson's disease who were all of the young‐onset type. Two patients had developed response fluctuations after the use of levodopa, with severe hypokinesia, painful dystonia, and rigidity in the “off” phase and violent dyskinesias in the “on” phase. One patient, in a continuous hypokinetic rigid state, was totally unresponsive to dopaminergic medication. All were at Hoehn and Yahr stage 5 in the “off” phase before surgery. After surgery, the hypokinetic state was reversed and dyskinesias were abolished in all patients. Hoehn and Yahr stages were 3 in the “off” phase postoperatively. Overall functional improvement was marked and lasting after follow‐up for 7, 12, and 13 months, respectively. Complications were visual field deficit and transient central facial paresis, both in the same patient. Bilateral posteroventral pallidotomy can ameliorate response fluctuations, hypokinesia, rigidity, and painful dystonia in advanced Parkinson's disease.

Url:

https://api.istex.fr/document/5EB2019F253C82A9BBA4FA8F4C7F5AF96D6D638F/fulltext/pdf

DOI: 10.1002/mds.870120521

Affiliations:

Le document en format XML

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<term>Drug Resistance</term>
<term>Dyskinesia, Drug-Induced (surgery)</term>
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<front><div type="abstract" xml:lang="en">In this report, we describe the effect of staged bilateral posteroventral pallidotomy in three patients with advanced Parkinson's disease who were all of the young‐onset type. Two patients had developed response fluctuations after the use of levodopa, with severe hypokinesia, painful dystonia, and rigidity in the “off” phase and violent dyskinesias in the “on” phase. One patient, in a continuous hypokinetic rigid state, was totally unresponsive to dopaminergic medication. All were at Hoehn and Yahr stage 5 in the “off” phase before surgery. After surgery, the hypokinetic state was reversed and dyskinesias were abolished in all patients. Hoehn and Yahr stages were 3 in the “off” phase postoperatively. Overall functional improvement was marked and lasting after follow‐up for 7, 12, and 13 months, respectively. Complications were visual field deficit and transient central facial paresis, both in the same patient. Bilateral posteroventral pallidotomy can ameliorate response fluctuations, hypokinesia, rigidity, and painful dystonia in advanced Parkinson's disease.</div>
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Movement Disorders (revue)

Bilateral posteroventral pallidotomy in advanced parkinson's disease in three patients

Bilateral posteroventral pallidotomy in advanced parkinson's disease in three patients

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.